Multiple Antibody Response to Repeated Transfusions
نویسندگان
چکیده
منابع مشابه
CTLA4Ig inhibits alloantibody responses to repeated blood transfusions.
Allosensitization is a fundamental problem that limits the effectiveness of blood transfusions. Patients who receive multiple transfusions of blood or blood components frequently develop alloantibodies against donor alloantigens. Allosensitized patients are refractory to further transfusion and difficult to transplant successfully. CTLA4Ig fusion protein, which blocks the CD28-B7 costimulatory ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1950
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4665.1299